Unit 6: Analysis of Complex Data (Metabolism & Networks)

Featured Software: Cluster and TreeView

Suggested Reading

Gibas Ch. 11 (annotation, functional genomics) pp. 307-328
Gibas Ch. 14 (data preparation and mining) pp. 383-385, 396-402
Drug Discovery: A Historical Perspective.
Gene Expression Data Mining.
Probing Protein Interactions.
The digital code of DNA.

Discussion

Overview of Computational Cell Biology.

Exercise

Making Connections.

Unit Project

Analysis of "Cluster analysis and display of genome-wide expression patterns", by Michael Eisen, Paul Spellman, Patrick Brown and David Botstein (1998) Proc. Natl. Acad. Sci. USA 95: 14863-14868.
Click here for project details.