Unit 2: Genome Sequencing, Mapping, and Comparison

Featured Software: PERL AND BIOPERL

Recommended Reading

Gibas and Jambeck Text
Chapter 2 pp. 22-26 (central dogma review)
Chapter 7 pp. 159-172 (sequence analysis primer)
Chapter 11 pp. 294-310 (genome sequencing and annotation)
Chapter 12 pp. 331-349 (data analysis with PERL)

Articles of Interest
Sequencing the Human Genome
Evolving genomic metaphors: a new look at the language of DNA
The genome chose its alphabet with care
Creating a bioinformatics nation: Exploiting genomic data
More on selected topics

Exercises and Activities

Genome sequencing activity
Discussion of annotation
Contig assembly, annotation software
PERL and BIOPERL activity

Unit Project

Comparative Genomics of Plants
Background Article

Useful Links: Resource Guide | Tree of Life | Rubric